ALPHASUITEATLASTM
PDB 8ELT
X-RAY DIFFRACTION · 1.66 Å
Descriptions refer to the mapped proteins, not necessarily the full deposited construct or assembly.
P01112 · Chains A
Homo sapiens
Signal transducer in the Ras-MAPK signaling pathway that regulates cell proliferation and survival [1]. Ras proteins bind GDP/GTP and possess intrinsic GTPase activity [2, 3, 4]. Recognized by LZTR1 that mediates its ubiquitination by a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex [5]
UniProt · P01112 · Snapshot 10/11/2026
Mappings below identify source-linked proteins. They do not establish residue-level annotation coverage or direct binding.
PROTEIN · Chains A
Homo sapiens
LIGAND · Chains B, D
No UniProt mapping provided
LIGAND · Chains C
No UniProt mapping provided
LIGAND · Chains E, F
No UniProt mapping provided
Protein annotations are displayed in the viewer only where residue mappings are verified. Domain annotations do not apply to DNA or RNA.
author defined assembly
Component membership checked · Chains A, B, C, D, E, F
Open assembly 1 →Allosteric site variants affect GTP hydrolysis on Ras.
Paper date: 10/2023Snapshot updated 09/11/2026. Source descriptions are attributed below; Atlas combines and displays their annotations.
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